PRP (Platelet Rich Plasma) and GFC (Growth Factor Concentrate) are popular hair loss treatments that use components derived from a patient’s own blood to strengthen hair follicles and reduce hair fall. PRP delivers platelet-rich plasma containing growth factors, while GFC uses a more refined process to isolate pure growth factors, offering higher consistency and often faster results.
PRP is commonly recommended for early-stage hair thinning and gradual improvement, whereas GFC is preferred for moderate hair loss, quicker response, and more predictable outcomes. The choice between PRP and GFC depends on the cause and severity of hair loss, response to previous treatments, and individual goals.
At Welona Skin, Hair, Body, and Laser Clinic in Chennai, dermatologists assess scalp health and hair loss patterns to recommend the most suitable option, ensuring safe, personalised, and realistic treatment outcomes.

Hair fall and thinning have become increasingly common concerns in Chennai. Stressful lifestyles, hormonal imbalance, nutritional deficiencies, pollution, and genetic factors often accelerate hair loss at an early age. While shampoos and supplements may help temporarily, many people eventually look for medical hair regrowth treatments that work at the follicle level.
This guide explains the difference between PRP and GFC, how each works, who should choose which hair regrowth treatment, and what dermatologists in Chennai recommend based on real clinical outcomes.
Understanding PRP and GFC for Hair Regrowth Treatment
What Is PRP?
PRP stands for Platelet Rich Plasma. In this treatment, a small amount of your blood is drawn and processed to separate plasma rich in platelets. These platelets release growth factors that help:
- Improve blood supply to hair follicles
- Strengthen existing hair roots
- Reduce hair fall
- Support new hair growth
PRP has been used in dermatology for many years and is a well-established treatment for early to moderate hair thinning.
What Is GFC?
GFC stands for Growth Factor Concentrate. It is an advanced version of PRP. Instead of injecting whole platelet-rich plasma, GFC isolates pure growth factors from platelets using a specialised process.
This results in:
- Higher concentration of growth factors
- More consistency between sessions
- Less inflammatory components
- Better patient comfort
Because of this refinement, GFC is often considered a next-generation regenerative hair therapy. A recent research found that patients were highly satisfied with the results: faster rate of hair growth, better quality of hair, and minimal side effects.
PRP vs GFC: Key Differences Explained Simply
| Aspect | PRP | GFC |
| Source | Platelet-rich plasma | Pure Growth Factors |
| Concentration | Moderate | High & Standardised |
| Consistency | Varies by platelet count | Uniform dose |
| Pain and swelling | Mild to moderate | Usually less |
| Speed of results | Gradual | Often faster |
| Predictability | Variable | More consistent |
Both treatments aim to improve follicle health, but the purity and concentration of growth factors are what separate GFC from PRP.
How PRP and GFC Work as a Hair Regrowth Treatment
Both treatments stimulate hair follicles by improving their environment.
They help by:
- Increasing blood circulation to the scalp
- Delivering growth signals to weak follicles
- Extending the hair growth phase
- Improving hair thickness and density over time
However, because GFC delivers a more refined growth factor dose, dermatologists often see more predictable outcomes, especially in patients who did not respond well to PRP.
Which Hair Regrowth Treatment Works Faster?
Most people want to know which treatment works faster. Here is the breakdown.
- PRP usually shows a reduction in hair fall after 4 to 6 weeks, with visible improvement over a few months
- GFC often shows earlier improvement in hair texture, strength, and density due to higher growth factor activity
That said, the speed of results also depends on:
- Hair loss severity
- Underlying cause
- Lifestyle and nutrition
- Consistency of sessions
Who Should Choose PRP vs GFC?
| Choose PRP If | Choose GFC if |
| You have early-stage hair thinning | Hair fall is moderate or progressing |
| You had a limited response to PRP earlier | You want faster and more consistent results |
| You want a proven, cost-effective treatment | You had limited response to PRP earlier |
| You are comfortable with gradual improvement | You prefer a more refined and comfortable procedure |
| You are starting medical hair regrowth treatment | You want stronger follicle stimulation without variability |
PRP works well as a starting treatment for many patients, especially in early hair thinning. GFC is often recommended when hair loss is more advanced or when patients want quicker, more predictable results.
Why Choose Welona Skin, Hair, Body and Laser Clinic for PRP or GFC in Chennai
At Welona, hair regrowth treatments are planned with a medical and personalised approach, not a one-size-fits-all protocol.
What makes the difference:
- Dermatologist-led hair and scalp assessment
- Clear guidance on whether PRP or GFC suits you better
- Use of high-quality processing kits
- Personalised session planning
- Integration with other treatments like QR678, mesotherapy, or medical therapy when required
- Honest counselling on expectations and timelines
This ensures that patients choose the right hair regrowth treatment, not just the popular one.
To Wrap It UP
PRP and GFC are both effective regenerative treatments for hair loss, but they are not interchangeable. PRP is a reliable, proven option for early hair thinning, while GFC offers a more refined and consistent approach for those seeking faster and stronger results.
The right choice depends on your hair condition, response to treatment, and long-term goals. A dermatologist-guided evaluation ensures that you invest in the treatment that will benefit you the most.
When chosen and performed correctly, both PRP and GFC can significantly improve hair quality, density, and confidence over time.
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FAQ: PRP vs GFC
Is GFC better than PRP?
GFC offers more concentrated growth factors and often gives faster, more consistent results, but PRP is still effective in early hair loss.
Does PRP or GFC permanently regrow hair?
Neither permanently cures hair loss. They slow progression and improve density when done consistently.
Which treatment is less painful?
Most patients find GFC more comfortable due to its refined formulation.
How many sessions are needed?
Typically 3 to 6 sessions, depending on severity and response.
Can men and women do both treatments?
Yes. Both treatments are suitable for all genders.